Value of intravoxel incoherent motion magnetic resonance imaging for differentiating metastatic from nonmetastatic mesorectal lymph nodes with different short-axis diameters in rectal cancer
| Autor: | Haiping Zhang, Ling Long, Xinjie Liu, Dajing Guo, Xiaojing He, Jun Zhou |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Short axis Colorectal cancer Biopsy lcsh:RC254-282 Diagnosis Differential Motion medicine Humans magnetic resonance imaging Mesentery Radiology Nuclear Medicine and imaging In patient rectal cancer Lymph node Intravoxel incoherent motion Aged Neoplasm Staging intravoxel incoherent motion Mesorectal integumentary system medicine.diagnostic_test Rectal Neoplasms business.industry Reproducibility of Results Magnetic resonance imaging General Medicine Middle Aged lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Tumor Burden medicine.anatomical_structure ROC Curve Oncology Lymphatic Metastasis Female Lymph Nodes Lymph business Nuclear medicine mesorectal lymph node |
| Zdroj: | Journal of Cancer Research and Therapeutics, Vol 15, Iss 7, Pp 1508-1515 (2019) |
| ISSN: | 0973-1482 |
| DOI: | 10.4103/jcrt.jcrt_76_19 |
| Popis: | Background: Conventional magnetic resonance imaging (MRI) does not accurately evaluate lymph node (LN) status, which is essential for the treatment and prognosis assessment in patients with rectal cancer. Objective: The aim of this study is to evaluate the diagnostic value of intravoxel incoherent motion (IVIM) MRI in differentiating metastatic and nonmetastatic mesorectal LNs with different short-axis diameters in rectal cancer patients. Materials and Methods: Forty patients (154 LNs) were divided into three groups based on short-axis diameter: 3 mm ≤ × ≤5 mm, 5 mm < × ≤7 mm, and × >7 mm. MRI characteristics and IVIM parameters were compared between the metastatic and nonmetastatic LNs to determine the diagnostic value for discriminating them. Results: In the 3 mm ≤ × ≤ 5 mm group, mean D values were significantly lower in metastatic than in the nonmetastatic LNs (P < 0.001). In the 5 mm < × ≤7 mm group, mean f values were significantly lower in metastatic than nonmetastatic LNs (P < 0.05). In the × >7 mm group, only the short-axis diameter of metastatic LNs was significantly greater than that of nonmetastatic LNs (P < 0.05). The area under the curve, sensitivity, specificity, and cutoff values were used for differentiating the metastatic from the nonmetastatic LNs. Conclusion: IVIM parameters can differentiate metastatic from nonmetastatic LNs with smaller short-axis diameters (× ≤7 mm) in rectal cancer, and the short-axis diameter is a significant factor in identifying metastatic and nonmetastatic LNs in larger short-axis diameter groups (× >7 mm). |
| Databáze: | OpenAIRE |
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