Associations of dairy intake with risk of mortality in women and men: three prospective cohort studies
Autor: | Daniel I. Chasman, JoAnn E. Manson, Xuehong Zhang, Peter Kraft, Walter C. Willett, Christina Ellervik, Jorge E. Chavarro, Jun Li, Meir J. Stampfer, Kathryn M. Rexrode, Frank B. Hu, Lu Qi, Ming Ding |
---|---|
Rok vydání: | 2019 |
Předmět: |
Adult
Male 030309 nutrition & dietetics National Death Index 03 medical and health sciences 0302 clinical medicine Risk Factors Risk of mortality Humans Medicine Prospective Studies 030212 general & internal medicine Family history Prospective cohort study Proportional Hazards Models 2. Zero hunger 0303 health sciences business.industry Proportional hazards model Research Hazard ratio Repeated measures design General Medicine Middle Aged United States Confidence interval Diet 3. Good health Female Dairy Products business Follow-Up Studies Demography |
Zdroj: | The BMJ Ding, M, Li, J, Qi, L, Ellervik, C, Zhang, X, Manson, J E, Stampfer, M, Chavarro, J E, Rexrode, K M, Kraft, P, Chasman, D, Willett, W C & Hu, F B 2019, ' Associations of dairy intake with risk of mortality in women and men : Three prospective cohort studies ', The BMJ, vol. 367, l6204 . https://doi.org/10.1136/bmj.l6204 |
ISSN: | 1756-1833 0959-8138 |
Popis: | ObjectiveTo examine the association of consumption of dairy foods with risk of total and cause specific mortality in women and men.DesignThree prospective cohort studies with repeated measures of diet and lifestyle factors.SettingNurses’ Health Study, Nurses’ Health Study II, and the Health Professionals Follow-up Study, in the United States.Participants168 153 women and 49 602 men without cardiovascular disease or cancer at baseline.Main outcome measureDeath confirmed by state vital records, the national death index, or reported by families and the postal system. During up to 32 years of follow-up, 51 438 deaths were documented, including 12 143 cardiovascular deaths and 15 120 cancer deaths. Multivariable analysis further adjusted for family history of cardiovascular disease and cancer, physical activity, overall dietary pattern (alternate healthy eating index 2010), total energy intake, smoking status, alcohol consumption, menopausal status (women only), and postmenopausal hormone use (women only).ResultsCompared to the lowest category of total dairy consumption (average 0.8 servings/day), the multivariate pooled hazard ratio for total mortality was 0.98 (95% confidence interval 0.96 to 1.01) for the second category of dairy consumption (average 1.5 servings/day), 1.00 (0.97 to 1.03) for the third (average 2.0 servings/day), 1.02 (0.99 to 1.05) for the fourth (average 2.8 servings/day), and 1.07 (1.04 to 1.10) for highest category (average 4.2 servings/day; P for trend ConclusionThese data from large cohorts do not support an inverse association between high amount of total dairy consumption and risk of mortality. The health effects of dairy could depend on the comparison foods used to replace dairy. Slightly higher cancer mortality was non-significantly associated with dairy consumption, but warrants further investigation. |
Databáze: | OpenAIRE |
Externí odkaz: |