COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight

Autor: Sai-Juan Chen, Mehmet Ozturk, Michel Goldman, Denis Noble, Hiroaki Kitano, J. T. Paweska, James R. Heath, Doron Lancet, Karine Clément, Marcelo B. Soares, Mathias Uhlén, Damjana Rozman, Emiel F.M. Wouters, Christian Bréchot, Josep Roca, Ulrike Protzer, Ferran Sanz, Peter J. M. Openshaw, Olaf Wolkenhauer, Martine Laville, Antoine Magnan, Tolu Oni, Bartha Maria Knoppers, Peter J. Sterk, Ariel B. Lindner, Iruka N. Okeke, Myrna C. Bonaldo, Daria Danilenko, Alfonso Valencia, Bertrand Boutron, Rudi Balling, Samir K. Brahmachari, Andrea Gelemanovic, Sumio Sugano, Alberto Di Meglio, Edgar Morin, Jason D Goldman, Mihael H. Polymeropoulos, Christian Pristipino, Carole Goble, Sylvie van der Werf, Vincenzo Valentini, Ismail Serageldin, Laurent Nottale, Leroy Hood, Jesper Tegnér, S. Palkonen, Alfredo Cesario, Christophe Pison, Yi-Ke Guo, Andres Metspalu, Andrea Urbani, David Supple, Mark Lathrop, Laurent P. Nicod, Catherine Larue, Theresa J. Ochoa, Peter Hunter, Eran Segal, Manlio Vinciguerra, Niklas Blomberg, Lisa F. P. Ng, Helga Nowotny, Marc Santolini, Charles Auffray, Giulio Superti-Furga, Takashi Gojobori, Li Jin, Giovanni Scambia
Přispěvatelé: Pulmonology, European Institute for Systems Biology and Medicine (EISBM), University of Luxembourg [Luxembourg], ELIXIR Hub [Cambridge], Fundação Oswaldo Cruz / Oswaldo Cruz Foundation (FIOCRUZ), Réseau International des Instituts Pasteur (RIIP), CSIR Institute of Genomics and Integrative Biology [New Delhi] (IGIB), Global Virus Network, University of South Florida [Tampa] (USF), Fondazione Policlinico Universitario A. Gemelli [Rome] (FPUAG), Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart [Roma] (Unicatt), Shanghai Jiao Tong University School of Medicine, Nutrition et obésités: approches systémiques (UMR-S 1269) (Nutriomics), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Smorodintsev Research Institute of Influenza [Saint-Petersbourg, Russia], European Organization for Nuclear Research (CERN), Mediterranean Institute for Life Sciences [Split, Croatia] (MedILS), University of Manchester [Manchester], King Abdullah University of Science and Technology (KAUST), National Institute of Genetics [Mishima, Japan] (NIG), Providence St Joseph Health [Seattle], Université libre de Bruxelles (ULB), Imperial College London, Hong Kong Baptist University (HKBU), Institute for Systems Biology [Seattle] (ISB), University of Auckland [Auckland], Fudan University [Shanghai], The Systems Biology Institute [Tokyo] (SBI), Okinawa Institute of Science and Technology Graduate University (OIST), McGill University = Université McGill [Montréal, Canada], Weizmann Institute of Science [Rehovot, Israël], Luxembourg Institute of Health (LIH), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Centre de Recherche Interdisciplinaire / Center for Research and Interdisciplinarity [Paris, France] (CRI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), PHU 2 - Institut du Thorax et du Sytème Nerveux [CHU Nantes] (ITSN), Centre hospitalier universitaire de Nantes (CHU Nantes), University of Tartu, Association pour la Pensée Complexe [Montpellier], Observatoire de Paris - Site de Meudon (OBSPM), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Universidad Peruana Cayetano Heredia (UPCH), University of Ibadan, University of Cambridge School of Clinical Medicine, University of Cape Town, Dokuz Eylül Üniversitesi = Dokuz Eylül University [Izmir] (DEÜ), Université Grenoble Alpes (UGA), Technische Universität München = Technical University of Munich (TUM), Bibliotheca Alexandrina - Library of Alexandria, University of Illinois College of Medicine, University of Illinois System, University of Amsterdam [Amsterdam] (UvA), The University of Tokyo (UTokyo), The Open University of Japan [Chiba] (OUJ), Medizinische Universität Wien = Medical University of Vienna, Karolinska University Hospital [Solna, Sweden] (KUH), Royal Institute of Technology [Stockholm] (KTH ), Barcelona Supercomputing Center - Centro Nacional de Supercomputacion (BSC - CNS), Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses (GMV-ARN (UMR_3569 / U-Pasteur_2)), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre National de Référence des Virus des Infections Respiratoires (dont la Grippe) [Lyon] (CNR - laboratoire associé), Institut des Agents Infectieux [Lyon] (IAI), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), St. Anne’s University Hospital [Brno], University of Rostock, Maastricht University [Maastricht, Pays-Bas], Ludwig Boltzmann Institute for Lung Health [Vienna, Austria], This work was supported during its preparation phases by the State Key Laboratory of Medical Genomics, OverseasExpertise Introduction Project for Discipline Innovation [111 Project, B17029] to SJC, LH, CA, European Union grants CASyM [FP7-n°305033] to CA, RB, JR, DR, DS, JT, OW, eTRIKS (IMI-1-n°115446) to CA, RB, YG, PREPARE [FP7-n°602525] to CA, PO, SV, and initial funds in support of the deep phenotyping clinical study from philanthropic donors, Gilead, Merck and Novartis to JG, JH, LH, the Ricerca Corrente Program by the Italian Ministry of Health to AC, CPr, GS, AU, VV, the National Megaprojects of China for Infectious Diseases [2017ZX10103009-001, 2018ZX10305409-001-005], Double First-class projects from the Ministry of Education to the National Research Center for Translational Medicine Shanghai to SJC, Shanghai Municipal Science and Technology Major Project [2017SHZDZX01] to LJ., European Project: 305033,EC:FP7:HEALTH,FP7-HEALTH-2012-INNOVATION-1,CASYM(2012), European Project: 602525,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-1,PREPARE(2014)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Civil society
Economic growth
Distancing
[SDV]Life Sciences [q-bio]
viruses
Public administration
Intellectual property
Coalition
Coronavirus
Covid-19
Pandemic
Sars-cov-2
Solidarity
Systemic Crisis
Systemic Response
General Biochemistry
Genetics and Molecular Biology
03 medical and health sciences
0302 clinical medicine
Political science
0502 economics and business
media_common.cataloged_instance
030212 general & internal medicine
050207 economics
European union
General Pharmacology
Toxicology and Pharmaceutics
media_common
030304 developmental biology
Government
0303 health sciences
050208 finance
General Immunology and Microbiology
SARS-CoV-2
05 social sciences
Systemic crisis
Conflict of interest
Collective intelligence
virus diseases
COVID-19
General Medicine
There is no alternative
biochemical phenomena
metabolism
and nutrition
3. Good health
Alliance
13. Climate action
Honorarium
Systemic response
Zdroj: F1000Research, 9, 1-18. F1000 Research Ltd.
F1000 Res. 9:1130 (2021)
F1000Research
F1000Research, 2020, 9, pp.1130. ⟨10.12688/F1000RESEARCH.26098.1⟩
Auffray, C, Balling, R, Blomberg, N, Bonaldo, M, Boutron, B, Brahmachari, S, Bréchot, C, Cesario, A, Chen, S, Clément, K, Danilenko, D, Di Meglio, A, Gelemanovic, A, Goble, C, Gojobori, T, Goldman, J D, Goldman, M, Guo, Y, Heath, J, Hood, L, Hunter, P, Jin, L, Kitano, H, Knoppers, B M, Lancet, D, Larue, C, Lathrop, M, Laville, M, Lindner, A B, Magnan, A, Metspalu, A, Morin, E, Ng, L F P, Nicod, L, Noble, D, Nottale, L, Nowotny, H, Ochoa, T, Okeke, I, Oni, T, Openshaw, P, Oztürk, M, Palkonen, S, Paweska, J, Pison, C, Polymeropoulos, M, Pristipino, C, Protzer, U, Roca, J, Rozman, D, Santolini, M, Sanz, F, Scambia, G, Segal, E, Serageldin, I, Soares, M B, Sterk, P, Sugano, S, Superti-furga, G, Supple, D, Tegnér, J, Uhlen, M, Urbani, A, Valencia, A, Valentini, V, Van Der Werf, S, Vinciguerra, M, Wolkenhauer, O & Wouters, E 2020, ' COVID-19 and Beyond: A Call for Action and Audacious Solidarity to All the Citizens and Nations, It Is Humanity’s Fight ', SSRN Electronic Journal . https://doi.org/10.2139/ssrn.3630412
ISSN: 2046-1402
Popis: Background: SARS-CoV-2 belongs to a subgroup of coronaviruses rampant in bats for centuries. It has caused the COVID-19 pandemic. Most patients recover, but a minority of severe cases experience acute respiratory distress or an inflammatory storm devastating many organs that can lead to patient death. The spread of SARS-CoV-2 has been facilitated by the increasing intensity of air travel, urban congestion and human contact during the last half century. Until therapies and vaccines are available, tests for virus and exposure, confinement measures and physical distancing have helped curb the pandemic. Vision: The COVID-19 pandemic calls for safeguards and remediation measures through a systemic response. A myriad of self-organizing initiatives by scientists and citizens is developing an advanced collective intelligence response to the coronavirus crisis. Their integration forms Olympiads of Solidarity and Health. Their ability to optimize our response to COVID-19 could serve as a model to trigger a global metamorphosis of our societies with far-reaching consequences for attacking fundamental challenges facing humanity in the 21st century. Mission: For COVID-19 and these other challenges, there is no alternative but action. Meeting in Paris in 2003, we set out to "rethink research to understand life and improve health." We have now formed an international coalition of academia and industry ecosystems taking a systems medicine approach to understanding COVID-19 by thoroughly characterizing viruses, patients and populations during the pandemic, using openly shared tools. All results will be publicly available with no initial claims for intellectual property rights. This World Alliance for Health and Wellbeing will catalyze the creation of medical and health products such as diagnostic tests, drugs and vaccines that become common goods accessible to all, while seeking further alliances with civil society to bridge with socio-ecological and technological approaches that characterise urban systems, for a collective response to future health emergencies. Funding: This work was supported during its preparation phases by the State Key Laboratory of Medical Genomics, Overseas Expertise Introduction Project for Discipline Innovation (111 Project, B17029) to SJC, LH, CA; European Union grants CASyM (FP7-n°305033) to CA, RB, JR, DR, DS, JT, OW; eTRIKS (IMI-1-n°115446) to CA, RB, YG; PREPARE (FP7n°602525) to CA, PO, SV; and initial funds in support of the deep phenotyping clinical study from philanthropic donors, Gilead, Merck and Novartis to JG, JH, LH; the Ricerca Corrente Program by the Italian Ministry of Health to AC, CPr, GS, AU, VV; the National Megaprojects of China for Infectious Diseases (2017ZX10103009-001, 2018ZX10305409-001-005), Double Firstclass projects from the Ministry of Education to the National Research Center for Translational Medicine Shanghai to SJC; Shanghai Municipal Science and Technology Major Project (2017SHZDZX01) to LJ. Conflict of Interest: Rudi Balling reports being a founder/shareholder of ITTM S.A. and Megeno S.A., outside the submitted work, he is co-inventor and holder of two issued patents; James Heath reports personal fees and other from PACT Pharma, outside the submitted work; Hiroaki Kitano reports grants from Minister of Health, Welfare, and Labor of Japanese Government, grants from Okinawa Prefecture Government, outside the submitted work; Doron Lancet reports personal fees from Weizmann Institute of Science and LifeMap Science Inc., outside the submitted work; Catherine Larue reports personal fees from Genfit, outside the submitted work; Peter Openshaw reports personal fees for consultancy work with Janssen, JJ Susanna Palkonen reports grants from Aimmune, Astra Zeneca, Boehringer Ingelheim, Chiesi, DBV Technologies, GSK, Leo Pharma, Novartis, Pfizer, Regeneron Pharmaceuticals, Sanofi Genzyme, outside the submitted work, is employed by the EFA who receives unrestricted grants from corporate entities as above, represents EFA in the following advisory groups of these entities: Astra Zeneca COPD Advisory Committee, GSK Health Advisory Board and Novartis European Patient Advisory Group, receives no personal gain, honoraria, when applicable expenses are payed to her organization, is in a voluntary function the Chair of the Patient Access Partnership PACT who receives unrestricted grants from EFPIA, MedTech Europe, EUCOPE and Medicines for Europe for core operations, and project grants from individual companies, outside the submitted work; Christophe Pison reports personal fees and non-financial support from AstraZeneca, Boehringer Ingelheim, GSK, Novartis, outside the submitted work; Mihael Polymeropulos reports other from Vanda Pharmaceuticals, outside the submitted work; Ulrike Protzer reports grants from VIR Biotechnology, grants and non-financial support from Roche, grants from Alios-JJ Peter Sterk reports other from Breathomix BV, outside the submitted work; Giulio Superti-Furga reports being a shareholder of Proxygen GmbH, Haplogen GmbH and Allcyte GmbH, outside the submitted work; Vincenzo Valentini reports personal fees from Merck Serono, Betaglue, outside the submitted work; Sylvie van der Werf reports other from Sanofi Pasteur, outside the submitted work; she is the holder of four issued patents. The other authors have declared no conflict of interest.
Databáze: OpenAIRE
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