Biphasic decline of CD4 cell count during scheduled treatment interruptions
| Autor: | Jintanat Ananworanich, Catherine Fagard, Cédric Y. Bandelier, Bernard Hirschel, Felipe García, Huldrych F. Günthard, Thomas V. Perneger, Michelle Le Braz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
Sexually transmitted disease
medicine.medical_specialty Anti-HIV Agents/ administration & dosage Anti-HIV Agents Immunology HIV Infections Drug Administration Schedule Antiretroviral Therapy Highly Active medicine Antiretroviral treatment Immunology and Allergy Humans Prospective Studies Cd4 cell count ddc:616 business.industry HIV Infections/drug therapy/ immunology/virology Drug holiday Viral Load Surgery Antiretroviral Therapy Highly Active/methods CD4 Lymphocyte Count Infectious Diseases Anesthesia Viral disease business Viral load |
| Zdroj: | AIDS, Vol. 19, No 4 (2005) pp. 439-441 |
| ISSN: | 0269-9370 |
| Popis: | In 115 patients whose scheduled treatment interruptions (STI) lasted 24 weeks, the CD4 cell count declined by a median of 30 cells/ml/week during the first 4 weeks, compared with 3 cells/ml/week during the next 20 weeks. In multivariate regression, a pronounced early fall in CD4 cells correlated with a higher CD4 cell count at the start of STI, with more gain in CD4 cells during antiretroviral treatment preceding STI, and with a higher viral load at week 4. |
| Databáze: | OpenAIRE |
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