Correction: Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus)
Autor: | Klena Sarges Marruaz da Silva, Gyselly de Cássia Bastos de Matos, Rosane do Socorro Pompeu de Loiola, Délia Cristina Figueira Aguiar, Washington Luiz Assunção Pereira, Tereza Cristina de Oliveira Corvelo |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Physiology
030204 cardiovascular system & hematology Monkeys Biochemistry Epithelium Salivary Glands 0302 clinical medicine Immune Physiology Medicine and Health Sciences Primate Tissue Distribution Saimiri chemistry.chemical_classification Mammals Immune System Proteins Multidisciplinary biology Eukaryota Callithrix Body Fluids Platyrrhini Phenotypes Blood Organ Specificity Sapajus apella Vertebrates Aotidae Medicine Anatomy Aotus infulatus Research Article Primates Science 030231 tropical medicine Immunology ABO Blood-Group System 03 medical and health sciences Exocrine Glands Antigen Species Specificity biology.animal Genetic model Genetics Animals Pharmacokinetics Antigens Pharmacology New World monkeys Biology and life sciences Organisms Saimiri sciureus Proteins Correction biology.organism_classification Molecular biology Enzyme Biological Tissue chemistry Tissue expression Amniotes Zoology Digestive System Blood Groups |
Zdroj: | PLoS ONE, Vol 16, Iss 10, p e0259504 (2021) PLoS ONE, Vol 15, Iss 11, p e0241487 (2020) PLoS ONE PLoS ONE, Vol 16, Iss 10 (2021) |
ISSN: | 1932-6203 |
Popis: | ABH antigens are histo-antigens, but were first described on the surface of human erythrocytes. They are found in those cells only in great apes and humans, while in more primitive animals they are found in tissues and body fluids. ABH antigens are mainly distributed in tissues that are in contact with the external environment and may serve as ligands for pathogens in tissues or block their connection. Description of the distribution of these molecules in non-human primate tissues is restricted to a few tissues and species. This paper describes the expression of human A, B and H type antigens in different organs from four species of New World Primates, obtained from the Centro Nacional de Primatas, as well as comparing that expression with what has been described for humans. In this study, although the tissue description of the antigens is similar to the genetic model for humans, some differences in expression between some organs from those species and those of humans were found. The differences occurred mainly in endodermal organs that have secretory functions and are probably under the control of the human-type FUT-2 enzyme. In the mesodermal-origin organs there was a reduction or absence of A and B antigen marking, particularly in the H precursor substance, indicating that those organs are under the control of the human-type FUT-1 enzyme. These findings have demonstrated that there is similar ABH antigen reactivity in tissue distribution between the species, although there are some species-specific cases. |
Databáze: | OpenAIRE |
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