Effect of lipid peroxidation, antioxidants, macro minerals and trace elements on eczema
| Autor: | Kaniz Fatema Liza, Mohammad Safiqul Islam, Jamiuddin Ahmed, Md. Shahid Sarwar, Md. Tareek Adnan, Mohammad Nurul Amin, Manjurul Islam Chowdhury, Mohammad Zahid Hossain |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Vitamin medicine.medical_specialty Antioxidant Adolescent medicine.medical_treatment Eczema Dermatology Antioxidants Lipid peroxidation Pathogenesis Young Adult chemistry.chemical_compound Malondialdehyde Internal medicine medicine Humans Minerals Vitamin C Case-control study General Medicine Middle Aged Ascorbic acid Trace Elements Endocrinology chemistry Biochemistry Case-Control Studies Female Lipid Peroxidation |
| Zdroj: | Archives of Dermatological Research. 307:617-623 |
| ISSN: | 1432-069X 0340-3696 |
| DOI: | 10.1007/s00403-015-1570-2 |
| Popis: | The exact etiology and pathogenesis of eczema are not yet fully understood, although different factors are considered as pathogenic mechanisms in the development of eczema. Our study was designed to determine extent of serum lipid peroxidation, antioxidants, macro minerals and trace elements in patients with eczema, and thereby, find any pathophysiological correlation. The study was conducted as a case–control study with 65 eczema patients as cases and 65 normal healthy individuals as controls. Lipid peroxidation was assessed by measuring the serum level of malondialdehyde (MDA). Antioxidants- vitamin A and E concentration was determined by RP-HPLC method whereas vitamin C was evaluated for serum ascorbic acid by UV spectrophotometric method. Serum macro minerals (Na, K, Ca) and trace elements (Zn, Fe) were determined by Atomic Absorption Spectroscopy (AAS). This study found significantly higher level of MDA (p |
| Databáze: | OpenAIRE |
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