Magneto-mechanical destruction of cancer-associated fibroblasts using ultra-small iron oxide nanoparticles and low frequency rotating magnetic fields
| Autor: | Véronique Gigoux, Nicolas Hallali, Pascal Clerc, Daniel Fourmy, Arnaud Hillion, Yoann Lalatonne, Nizar Serhan, Joana C. Antunes, Sara Lopez, Laurence Motte, Julian Carrey |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Materials science
business.industry General Engineering Bioengineering General Chemistry Low frequency equipment and supplies Atomic and Molecular Physics and Optics Magnetic field chemistry.chemical_compound chemistry Cancer-Associated Fibroblasts Optoelectronics General Materials Science business human activities Magneto Iron oxide nanoparticles |
| Zdroj: | Nanoscale advances. 4(2) |
| ISSN: | 2516-0230 |
| Popis: | The destruction of cells using the mechanical activation of magnetic nanoparticles with low-frequency magnetic fields constitutes a recent and interesting approach in cancer therapy. Here, we showed that superparamagnetic iron oxide nanoparticles as small as 6 nm were able to induce the death of pancreatic cancer-associated fibroblasts, chosen as a model. An exhaustive screening of the amplitude, frequency, and type (alternating |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|