Quantitative evaluations of male pattern baldness
Autor: | K. Adachi, K. Okazaki, N. Hanzawa, Makoto Uzuka, Sadao Imamura, Akihiro Ishino, Yoshiharu Tsuji |
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Rok vydání: | 1994 |
Předmět: |
Adult
Male medicine.medical_specialty Time Factors Quantitative Evaluations Physiology Dermatology Biology Biochemistry Double blind Hair growth Double-Blind Method Internal medicine Evaluation methods otorhinolaryngologic diseases medicine Image Processing Computer-Assisted Humans Molecular Biology integumentary system Alopecia Middle Aged medicine.disease Endocrinology Male-pattern baldness sense organs Hair |
Zdroj: | Journal of dermatological science. |
ISSN: | 0923-1811 |
Popis: | Several methods for the evaluation of hair growth have been reported; however, none of the hitherto reported methods are satisfactory as unbiased double blind studies to evaluate the efficacy of hair growth agents. In the present paper, we describe quantitative evaluation methods for hair growth by measuring the anagen ratio and hair diameters in 56 Japanese subjects aged 23-56 for 3 years. The average anagen ratio decreased by 3.8% in 3 years. The average hair diameters showed a statistically significant decrease each year totalling 3.4 microns. Subjects were sorted according to their anagen ratio into 4 groups. Each group showed different distribution patterns of hair diameters. The higher anagen ratio group has a high frequency peak at thicker hair diameters and the lower anagen ratio group has a high frequency peak at thinner hair diameters. The number of thicker hairs decreased and the high frequency peak shifted to thinner hair diameters in 3 years. These methods are useful to evaluate both the progression of male pattern baldness and the effects of hair growth agents with double blind studies in an unbiased quantitative fashion. |
Databáze: | OpenAIRE |
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