Dengue: setting the global research agenda

Autor: Michael B. Nathan, Axel Kroeger
Rok vydání: 2006
Předmět:
Zdroj: Lancet (London, England). 368(9554)
ISSN: 1474-547X
Popis: The global incidence of dengue has increased exponentially over past decades. Fuelled by conditioning factors such as rapid urbanisation demographic change large-scale migration and travel the disease is now endemic in most countries of the tropics and about 925 million people now live in urban areas that are at risk of dengue infection. The increasing incidence intensity and geographical expansion of dengue epidemics pose a growing threat to the health and economic well-being of populations living in endemic areas where the introduction of new virus strains to regions affected by existing serotypes is a risk factor for outbreaks and severe disease. Dengue is a major international public-health concern as expressed in World Health Assembly resolution WHA 55.17 and in the 2005 revision of the International Health Regulations (WHA 58.3). We do have strategies methods and guidelines with which we can greatly reduce dengue case-fatality rates and virus transmission but weak implementation of these plans and an inability to respond effectively to conditioning factors (such as those mentioned above) outside the health sector is causing concern. (excerpt)
Databáze: OpenAIRE