Postnatal Growth Disadvantage of the Small for Gestational Age Preterm Twins

Autor: Orit Pinhas-Hamiel, Orly Stern Levkovitz, Iris Morag, Mor Frisch, Tzipi Strauss, Maya Siman-Tov
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Adult
Male
medicine.medical_specialty
Birth weight
growth
Postnatal growth failure
Gestational Age
lcsh:TX341-641
Weight Gain
Article
preterm infant
Tertiary Care Centers
Young Adult
03 medical and health sciences
small for gestational age
Child Development
0302 clinical medicine
Pregnancy
Risk Factors
twin
030225 pediatrics
medicine
Birth Weight
Humans
030212 general & internal medicine
Postnatal growth
Retrospective Studies
Chi-Square Distribution
Nutrition and Dietetics
Obstetrics
business.industry
Age Factors
Infant
Newborn
Gestational age
Retrospective cohort study
Middle Aged
medicine.disease
Head circumference
Logistic Models
Infant
Small for Gestational Age
Referral center
Small for gestational age
Female
business
Head
lcsh:Nutrition. Foods and food supply
Infant
Premature
Food Science
Zdroj: Nutrients, Vol 10, Iss 4, p 476 (2018)
Nutrients; Volume 10; Issue 4; Pages: 476
Nutrients
ISSN: 2072-6643
Popis: In this study, we examined early growth characteristics among small-for-gestational-age (SGA) preterm twins compared to their appropriate-for-gestational-age (AGA) counterparts. A retrospective study evaluated all consecutive twins born between 2008 and 2015 at a tertiary referral center whose gestational age ranged from 30.0 to 34.86 weeks. Included were twins in which one twin was AGA and the other SGA at birth. Changes of ≥2, 1–1.99, and 0–0.99 in z-score between births and 36 weeks post menstrual age (PMA) were respectively defined as severe, moderate, and mild postnatal growth failure (PNGF) in weight or head circumference (HC). Early neonatal morbidities were documented. Multiple logistic regression analysis was applied to determine conditions associated with PNGF and its severity. Out of 666 sets of twins, 83 met the inclusion criteria. Weight PNGF was similar and mild among the SGA and the AGA groups (0.9 ± 0.46 vs. 0.96 ± 0.44 z-score, respectively, p = 0.24). At 36 weeks PMA, a significantly larger proportion of SGAs were below −2 z-scores in weight (84.3%) compared to birth (31.3%) or to the AGAs (8.4%). In both groups, weight PNGF correlated with the time needed to regain birth weight. HC PNGF was mild among both groups, yet significantly more prominent among the AGAs (0.39 ± 0.72 z-score) vs. SGAs (0.75 ± 0.65 z-score, p = 0.001). We suggest that among preterm SGA infants, the absolute z-score should be used to assess the severity of weight PNGF. Individual nutritional strategies to decrease time to regain birth weight may mitigate severe malnutrition among SGAs.
Databáze: OpenAIRE
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