Effect of Body Mass Index on Estimated Glomerular Filtration Rate Levels in Children With Congenital Solitary Kidney: A Cross-Sectional Multicenter Study
| Autor: | Emanuele Miraglia del Giudice, Daniela Capalbo, Laura Liguori, Giuseppina Campana, Chiara De Mutiis, Andrea Pasini, Claudio La Scola, Pierluigi Marzuillo, Angela La Manna, Andrea Pession, Francesca Mencarelli, Anna Di Sessa, Cristina Bertulli, Stefano Guarino |
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| Přispěvatelé: | La Scola, C., Guarino, S., Pasini, A., Capalbo, D., Liguori, L., Di Sessa, A., Bertulli, C., Mencarelli, F., De Mutiis, C., Campana, G., La Manna, A., Miraglia del Giudice, E., Pession, A., Marzuillo, P. |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Birth weight Population 030232 urology & nephrology Medicine (miscellaneous) Renal function Overweight Body Mass Index Solitary Kidney 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Obesity Child education education.field_of_study 030109 nutrition & dietetics Nutrition and Dietetics business.industry medicine.disease Cross-Sectional Studies Blood pressure Nephrology medicine.symptom Underweight business Body mass index Glomerular Filtration Rate |
| Zdroj: | Journal of Renal Nutrition. 30:261-267 |
| ISSN: | 1051-2276 |
| Popis: | Rationale & Objective: The objective of this study is to evaluate the effect of body mass index (BMI) on estimated glomerular filtration rate (eGFR) levels in children with congenital solitary kidney (CSK). Moreover, we evaluated if other factors could influence this relationship. Study Design: Multicenter cross-sectional study. Setting & Participants: University hospital pediatrics departments. Subjects: Two hundred eighty-one patients with CSK. Predictors: Weight, height, BMI-SDS (standard deviation score), duration of overweight/obesity, pubertal stage, systolic (SBP) and diastolic (DBP) blood pressure, eGFR, and renal ultrasound were obtained at the last follow-up visit. The population was classified on the basis of nutritional status and divided in tertiles for duration of overweight/obesity. We compared eGFR levels among these categories. A simple regression was used to correlate eGFR with BMI-SDS. To evaluate if other factors could influence the relationship between eGFR and BMI-SDS, a general linear model was performed, including gender, birth weight |
| Databáze: | OpenAIRE |
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