Disturbances of bilirubin metabolism
| Autor: | Cristina Bellarosa, Claudio Tiribelli |
|---|---|
| Přispěvatelé: | CJ Hawkey, J Bosch, JECJ Hawkey, J Bosch, JE Richter, G Garcia-Tsao, FKL Chan., Bellarosa, Cristina, Tiribelli, Claudio |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Dubin–Johnson syndrome
Gilbert Syndrome Gilbert syndrome medicine.medical_specialty Bilirubin business.industry UGT1 gene Bilirubin metabolism UGT1 gene Crigler–Najjar syndrome types I and II Gilbert syndrome Dubin–Johnson syndrome Rotor syndrome Phototherapy Metabolism Phototherapy medicine.disease Rotor syndrome Crigler–Najjar syndrome types I and II chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine business Bilirubin metabolism |
| Zdroj: | Textbook of Clinical Gastroenterology and Hepatology, Second Edition |
| Popis: | The inherited disorders of bilirubin metabolism are syndromes where the cause of hyperbilirubinemia is related to a genetic disorder of bilirubin transport and metabolism. They may be classified as unconjugated and conjugated hyperbilirubinemias: the first are Gilbert syndrome and Crigler–Najjar syndrome types I and II, and the second Dubin–Johnson and Rotor syndromes. Gilbert syndrome is the most common familial hyperbilirubinemia, while the others are rare. The most severe is Crigler–Najjar syndrome type I because of the possibility of neurological damage. All the other syndromes have an excellent prognosis. |
| Databáze: | OpenAIRE |
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