Additional file 4 of Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer

Autor: Hoover, Alyssa A., Hufnagel, Demetra H., Harris, Whitney, Kennady Bullock, Glass, Evan B., Liu, Esther, Barham, Whitney, Crispens, Marta A., Dineo Khabele, Giorgio, Todd D., Wilson, Andrew J., Yull, Fiona E.
Rok vydání: 2020
DOI: 10.6084/m9.figshare.13064454.v1
Popis: Additional file 4. Histological differences between IKFM and control tumors in established ID8-Luc tumors. C57BL/6 IKFM and control mice injected with ID8-Luc cells were treated with metronomic 1 g/L dox (5 days on, 2 days off per week) over a period of 30–60 days post-tumor cell injection (in red). A) Schematic of experimental design. B) Harvested omental tumor weight and C) Ascites volume at sacrifice. Values are mean + SEM. D) Representative low-power 4x magnification H&E images of control and IKFM tumors, with high-power 20x images of the boxed areas.
Databáze: OpenAIRE