Clinical Significance and Prognosis of Right Heart Thrombi Associated With Acute Pulmonary Thromboembolism ― Results of a Multicenter Registry of Thrombolysis in Japan ―
| Autor: | Yuko Onishi, Natsumi Harada, Takayuki Onishi, Isshi Kobayashi, Yasuhiro Satoh, Akihiro Niwa, Hirotaka Muramoto, Takashi Musha |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Hemodynamics 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Japan Internal medicine Humans Medicine Thrombolytic Therapy In patient Clinical significance Registries 030212 general & internal medicine Retrospective Studies business.industry Standard treatment Acute pulmonary thromboembolism Thrombosis General Medicine Thrombolysis Prognosis Heart Arrest Acute Disease Right heart Cardiology Pulmonary Embolism Cardiology and Cardiovascular Medicine business Plasminogen activator |
| Zdroj: | Circulation Journal. 85:353-360 |
| ISSN: | 1347-4820 1346-9843 |
| DOI: | 10.1253/circj.cj-20-0501 |
| Popis: | BACKGROUND Thrombolytic therapy is standard treatment in acute pulmonary thromboembolism (PTE) with hemodynamic instability. Although right heart thrombi (RHT) appear to increase mortality in acute PTE, large-scale studies of acute PTE with RHT are scarce.Methods and Results:Patient data (from August 2005 to May 2014) obtained from post-marketing surveillance of thrombolytic therapy using a tissue-type plasminogen activator were analyzed retrospectively. Of the 2,698 confirmed cases of acute PTE who underwent echocardiographic assessment, 166 (6.2%) were diagnosed with RHT. PTE patients with RHT, compared with those without RHT, had higher rates of mortality (20.2% vs. 10.4%, P |
| Databáze: | OpenAIRE |
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