Primary langerhans cell histiocytosis of the vulva
Autor: | Eudokia Mandala, Ioannis Venizelos, Zoi A. Tatsiou, Vassilios Acholos, Michael Goutzioulis |
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Rok vydání: | 2005 |
Předmět: |
Female circumcision
Pathology medicine.medical_specialty Disease Pathology and Forensic Medicine Vulva Antigens CD1 Langerhans cell histiocytosis medicine Biomarkers Tumor Left labium minus Humans business.industry S100 Proteins Obstetrics and Gynecology Middle Aged medicine.disease Combined Modality Therapy Histiocytosis Langerhans-Cell medicine.anatomical_structure Treatment Outcome Local radiotherapy Immunohistochemistry Surgical excision Female Radiotherapy Adjuvant Vulvar Diseases business |
Zdroj: | International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 25(1) |
ISSN: | 0277-1691 |
Popis: | Langerhans cell histiocytosis (LCH) of the female genital tract is very rare. A review of the literature revealed that only 12 cases of primary vulvar LCH have previously been published. We describe an additional case of LCH in which the disease was confined to the vulva. A 64-year-old woman was admitted to our hospital with a nodular mass on her left labium minus, and complete surgical excision was performed. On histological and immunohistochemical examination, the tumor fulfilled the criteria of LCH. A metastatic workup did not reveal any evidence of disease beyond the vulva. The patient received local radiotherapy, and 22 months later she is in excellent condition without local recurrence or metastatic disease. |
Databáze: | OpenAIRE |
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