A pilot study of a neuroendocrine test battery in posttraumatic stress disorder
| Autor: | Mamoun Mobayed, Siobhan Barry, Ivor Brown, Timothy G. Dinan, Lakshmi N. Yatham |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
medicine.medical_specialty Hydrocortisone Pilot Projects Dexamethasone Buspirone Stress Disorders Post-Traumatic Internal medicine Desipramine medicine Humans Biological Psychiatry Depression (differential diagnoses) Psychiatric Status Rating Scales Middle Aged Prolactin Test (assessment) Posttraumatic stress Growth Hormone Dexamethasone suppression test Female Psychology Hormone medicine.drug Clinical psychology |
| Zdroj: | Biological Psychiatry. 28:665-672 |
| ISSN: | 0006-3223 |
| DOI: | 10.1016/0006-3223(90)90453-9 |
| Popis: | Eight female patients who fulfilled DSM-III criteria for posttraumatic stress disorder (PTSD) took part in this study. They were each assessed using the dexamethasone suppression test, the desipramine/growth hormone stimulation test, which examines alpha-2-adrenoceptor functioning, and the buspirone/prolactin test, which is thought to examine 5-HT receptor functioning. A control group consisting of age- and sex-matched healthy subjects was also tested. For each subject the three tests were conducted over 5 days. Hormone assays were carried out blind to diagnosis. Overall no differences on any of the three tests were detected between the patients and controls. The results do not support a link between PTSD and major depression. |
| Databáze: | OpenAIRE |
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