ENDOGENOUS ENDOPHTHALMITIS IN THE SETTING OF COVID-19 INFECTION
| Autor: | Thibaud Mathis, Laurent Kodjikian, Alper Bilgic, Francesc March de Ribot, Rohit Yogi, Jesús Hernán González-Cortés, Aditya Sudhalkar |
|---|---|
| Přispěvatelé: | Matériaux, ingénierie et science [Villeurbanne] (MATEIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL) |
| Rok vydání: | 2021 |
| Předmět: |
Male
Visual acuity Stenotrophomonas maltophilia medicine.medical_treatment Antibiotics Vitrectomy medicine.disease_cause Eye Infections Bacterial [SPI.MAT]Engineering Sciences [physics]/Materials chemistry.chemical_compound 0302 clinical medicine Endophthalmitis Blood culture 030212 general & internal medicine medicine.diagnostic_test General Medicine Middle Aged Staphylococcal Infections Anti-Bacterial Agents 3. Good health Klebsiella pneumoniae COVID-19 Nucleic Acid Testing Female medicine.symptom Adult Methicillin-Resistant Staphylococcus aureus medicine.medical_specialty medicine.drug_class 03 medical and health sciences Tocilizumab Internal medicine medicine Humans Glucocorticoids Aged SARS-CoV-2 business.industry COVID-19 medicine.disease Methicillin-resistant Staphylococcus aureus Klebsiella Infections Vitreous Body Ophthalmology Pneumonia chemistry 030221 ophthalmology & optometry Gram-Negative Bacterial Infections business |
| Zdroj: | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2021, 41, pp.1709-1714. ⟨10.1097/IAE.0000000000003168⟩ |
| ISSN: | 0275-004X |
| Popis: | To describe endogenous endophthalmitis in the setting of COVID-19 pneumonia.Patients recovering from COVID-19 pneumonia who presented to our department with any or all of the following complaints: pain, watering, redness, and decreased vision were identified. All relevant data were collected for analysis.Three patients with endogenous endophthalmitis were identified. All patients had been treated for COVID-19 pneumonia and therefore had received remdesivir and systemic steroids; 2 of the 3 patients received tocilizumab. All patients received vitreous biopsy, vitrectomy, and intraocular antibiotic injection. Patient 1 demonstrated Klebsiella pneumoniae in blood culture, K. pneumoniae and Escherichia coli in urine culture, and K. pneumoniae in vitreous fluid, whereas Patients 2 and 3 demonstrated Stenotrophomonas maltophilia and methicillin-resistant Staphylococcus aureus in the blood and nasopharyngeal culture, respectively. Correspondingly, the same organism was cultured from vitreous in Patients 2 and 3. The visual acuity at the last follow-up in Patients 1 to 3 was 20/100, 20/80, and 20/40, respectively. The probable source of infection was identified in each as renal calculi, dental caries, and the pharynx, respectively. Real-time polymerase chain reaction demonstrated the presence of Severe Acute Respiratory Syndrome Coronavirus 2 in the vitreous fluid of Patient 1.We report good outcomes of early intervention for endogenous endophthalmitis in the setting of COVID-19 infection. We also document the presence of SARS-CoV-2 in vitreous. |
| Databáze: | OpenAIRE |
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