Long-term diagnostic value of MRI in detecting recurrent aggressive fibromatosis at two multidisciplinary sarcoma centers
| Autor: | Sam Sedaghat, Maya Sedaghat, Benjamin Reichardt, Olav Jansen, Kai Freund, Arne Streitbürger, Sebastian Krohn |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Medizin Postoperative mri Diagnostic accuracy Fibroma Thigh Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences Young Adult 0302 clinical medicine medicine Humans Radiology Nuclear Medicine and imaging Pathological business.industry Significant difference Sarcoma General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Axilla Fibromatosis Aggressive medicine.anatomical_structure 030220 oncology & carcinogenesis Aggressive fibromatosis Radiology Neoplasm Recurrence Local business |
| Zdroj: | European journal of radiology. 134 |
| ISSN: | 1872-7727 |
| Popis: | Purpose To assess the diagnostic accuracy of MRI in detecting recurrent aggressive fibromatosis (AF) during long-term follow-up at two multidisciplinary sarcoma centers. Methods Seventy-nine patients from two sarcoma centers were included in this IRB-approved study and were examined postoperatively using 1.5-T MRI. MRI follow-up scans were reviewed for true-positive/-negative and false-positive/-negative results. Available pathological reports and MRI follow-ups were set as reference. Results The median age of the patients was 38.1 ± 15.3 years. Of the patients 27.9 % showed recurrent AF lesions. The most common localizations of AF were the axilla/shoulder (n = 15) and the thigh (n = 11). From 498 postoperative MRI follow-ups, 24 true-positive, 16 false-positive, 6 false-negative, and 452 true-negative MRI follow-ups were identified. The overall sensitivity and specificity for detecting recurrent AF was 80 % and 97 %, respectively. There was no significant difference in the diagnostic accuracy at the two sarcoma centers. All false-negative results were found in small lesions. False-positive results mostly mimicked streaky (n = 10) and small ovoid/nodular (n = 5) lesions. The configuration of recurrent AF was significantly most often fascicular (50 %; p = 0.001−0.005). Conclusion MRI shows a high long-term diagnostic value in detecting AF recurrences. Nevertheless, radiologists should pay close attention when lesions are small, as they may remain undetected. Although the configuration of recurrent AF is most often fascicular, recurrences may also appear in different shapes. |
| Databáze: | OpenAIRE |
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