Peak fat oxidation is positively associated with vastus lateralis CD36 content, fed-state exercise fat oxidation, and endurance performance in trained males
| Autor: | Andrew E. Kilding, Warren B. Leigh, Casey M. Watkins, Ed Maunder, Daniel J. Plews, Matthew J Brick, Wee Leong Chang, Gareth A. Wallis, Tom Stewart |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
CD36 Antigens Male medicine.medical_specialty Sports medicine Physiology Performance CD36 Citrate (si)-Synthase Oxygen Consumption Fat oxidation Physiology (medical) Internal medicine medicine Humans Citrate synthase Orthopedics and Sports Medicine Muscle Skeletal biology business.industry Public Health Environmental and Occupational Health VO2 max Skeletal muscle Cycling General Medicine Lipid Metabolism Endocrinology medicine.anatomical_structure Athletes Physical Endurance biology.protein Muscle Original Article Fat metabolism business Oxidation-Reduction Federal state |
| Zdroj: | European Journal of Applied Physiology |
| ISSN: | 1439-6327 1439-6319 |
| DOI: | 10.1007/s00421-021-04820-3 |
| Popis: | Purpose Whole-body fat oxidation during exercise can be measured non-invasively during athlete profiling. Gaps in understanding exist in the relationships between fat oxidation during incremental fasted exercise and skeletal muscle parameters, endurance performance, and fat oxidation during prolonged fed-state exercise. Methods Seventeen endurance-trained males underwent a (i) fasted, incremental cycling test to assess peak whole-body fat oxidation (PFO), (ii) resting vastus lateralis microbiopsy, and (iii) 30-min maximal-effort cycling time-trial preceded by 2-h of fed-state moderate-intensity cycling to assess endurance performance and fed-state metabolism on separate occasions within one week. Results PFO (0.58 ± 0.28 g.min−1) was associated with vastus lateralis citrate synthase activity (69.2 ± 26.0 μmol.min−1.g−1 muscle protein, r = 0.84, 95% CI 0.58, 0.95, P |
| Databáze: | OpenAIRE |
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