A tunable scaffold of microtubular graphite for 3D cell growth
| Autor: | Mohammadreza Taale, Rainer Adelung, Carsten Grabosch, Matthias Mecklenburg, Ingo Paulowicz, Hannes Westerhaus, Ralph Lucius, Martina Böttner, Christine Selhuber-Unkel, Constanze Lamprecht, Karl Schulte, Arnim Schuchardt |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Scaffold Letter Materials science 3D scaffold Technische Fakultät Nanotechnology 02 engineering and technology Conjugated system aerographite cyclic RGD Polyethylene Glycols 03 medical and health sciences chemistry.chemical_compound Tissue engineering fibroblasts Cell Adhesion ddc:6 General Materials Science ddc:610 Cell adhesion Technik [600] Cells Cultured Phospholipids ddc:5 Tissue Scaffolds Cell growth 600: Technik Faculty of Engineering article Adhesion 021001 nanoscience & nanotechnology 030104 developmental biology chemistry tissue engineering ddc:540 Biophysics Surface modification Graphite ddc:620 0210 nano-technology Ethylene glycol ddc:600 3D scaffold aerographite cyclic RGD fibroblasts tissue engineering |
| Zdroj: | ACS Applied Materials and Interfaces 24 (8): 14980-14985 (2016-06-22) ACS Applied Materials & Interfaces.-Washington : ACS Publications; 2016.-S.14980-14985. ACS Applied Materials & Interfaces |
| Popis: | Aerographite (AG) is a novel carbon-based material that exists as a self-supportive 3D network of interconnected hollow microtubules. It can be synthesized in a variety of architectures tailored by the growth conditions. This flexibility in creating structures presents interesting bioengineering possibilities such as the generation of an artificial extracellular matrix. Here we have explored the feasibility and potential of AG as a scaffold for 3D cell growth employing cyclic RGD (cRGD) peptides coupled to poly(ethylene glycol) (PEG) conjugated phospholipids for surface functionalization to promote specific adhesion of fibroblast cells. Successful growth and invasion of the bulk material was followed over a period of 4 days. |
| Databáze: | OpenAIRE |
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