Comparing imaging capabilities of spectral domain and swept source optical coherence tomography angiography in healthy subjects and central serous retinopathy

Autor: Anthony J. Deegan, Jun Chang, Ruikang K. Wang, Qinqin Zhang, Fupeng Wang
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Eye and Vision, Vol 5, Iss 1, Pp 1-9 (2018)
Eye and Vision
ISSN: 2326-0254
DOI: 10.1186/s40662-018-0113-2
Popis: Background There are two forms of system implementation of optical coherence tomography angiography (OCTA) in ophthalmic imaging, i.e., spectral domain (SD-) and swept source OCTA (SS-OCTA). The purpose of this paper is to compare the SD-OCTA and SS-OCTA for elucidating structural and vascular features associated with central serous retinopathy (CSR), and to evaluate the effects of CSR on SD- and SS-OCTA’s imaging capabilities. Methods Normal subjects and CSR patients were imaged by SD- and SS-OCTA using 3 × 3 mm and 6 × 6 mm scan patterns. OCT signal strengths at the superficial retina, deep retina, Sattler’s layer and Haller’s layer were used to compare the ability of SD- and SS-OCTA to image structural features. In addition, the ability to acquire angiograms were discussed by evaluating retinal vessel density. Central serous volume (CSV) was measured and it was correlated with difference in signal strengths (∆S) between two OCTA devices. Results Seven normal eyes and seven diseased eyes were recruited. Results showed no significant differences between SD- and SS-OCT in detecting structural features of the retinal layer according to the paired t-test. However, when imaging the Sattler’s layer for normal eyes, a significant difference is found between SD- and SS-OCT (p
Databáze: OpenAIRE
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