Reproducibility of dynamic compliance and flow-volume curves in normal man
| Autor: | H. M. Brash, A. R. Guyatt, D. C. Flenley, J. A. Siddorn |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Adult
Male Time Factors Physiology Flow (psychology) Extrapolation Pulmonary compliance Physiology (medical) Linear regression Humans Lung Lung Compliance Maximal Expiratory Flow Rate Work of Breathing Mathematics Analysis of Variance Reproducibility business.industry Smoking Airway Obstruction Volume (thermodynamics) Dynamic compliance Female Lung Volume Measurements Pulmonary Ventilation Nuclear medicine business |
| Zdroj: | Journal of Applied Physiology. 39:341-348 |
| ISSN: | 1522-1601 8750-7587 |
| DOI: | 10.1152/jappl.1975.39.3.341 |
| Popis: | To evaluate methods proposed for the early detection of small airways obstruction. we have compared the precision of the forced expiratory flow-volume curve and of measurements of the frequency dependence of lung compliance in normal subjects, in 10 of whom these measurements were made on four occasions, and in 5 on two occasions. The maximal expiratory flow rate was highly reproducible, revealing consistent differences between these normal subjects, particularly when measured at 60% of TLC and corrected for differences in body size. The frequency-dependence measurements, expressed as the slope of the regression line relating dynamic compliance to frequency, showed much greater variation between repeated measurements in the same subject. Comparison with earlier published accounts is difficult in view of lack of quantitative data, but the variability between single measurements on different normal subjects appears to be similar to that which we have found when the results are expressed in a comparable manner. Dynamic compliance at a frequency of 1 Hz lay between 48% and 141% of the value obtained by extrapolation to zero frequency. |
| Databáze: | OpenAIRE |
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