The ribs in thalassemia. I. The relationship to therapy
| Autor: | R C Ablow, J P Lawson, H A Pearson |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male musculoskeletal diseases medicine.medical_specialty Adolescent Thalassemia Ribs Widened ribs Humans Transplantation Homologous Medicine Blood Transfusion Radiology Nuclear Medicine and imaging In patient Child Rib cage business.industry musculoskeletal system medicine.disease Surgery Radiography Normal ribs Regimen Child Preschool Female Bone Diseases Age of onset Abnormality Erythrocyte Transfusion business |
| Zdroj: | Radiology. 140:663-672 |
| ISSN: | 1527-1315 0033-8419 |
| Popis: | A spectrum of rib changes was seen in 32 patients with thalassemia. Eleven patients had normal ribs, and 21 patients demonstrated at least one abnormality. The rib changes in patients who had been treated with a low transfusion regimen (designed to maintain the hemoglobin level at 5-6 g/100 ml) were compared with the changes in patients who had been treated with a hypertransfusion regimen (designed to maintain the hemoglobin level above 9.4-19 g/100 ml). Ten of the 11 patients (91%) with normal ribs were younger than five years when first hypertransfused, while only three of the 21 patients (14%) with abnormal ribs were younger than five. The type of rib abnormality was related to the age of onset of the low transfusion regimen. Those patients with abnormal but nonwidened ribs had been started on the low transfusion regimen earlier than those patients with the same abnormality and widened ribs. Fifteen of the 21 patients showed regression of the abnormal findings; approximately two thirds of the rib abnormalities did not regress until after the onset of a hypertransfusion regimen. |
| Databáze: | OpenAIRE |
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