Repetitive DNA profile of the amphibian mitogenome
| Autor: | Jesús Javier Espinosa-Aguirre, Noel Cabañas, Tzipe Govezensky, Rafael Camacho-Carranza, David Romero, Arturo Becerra |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Amphibian
Mitochondrial DNA animal structures Base pair Inverted Repeat Sequences Biology lcsh:Computer applications to medicine. Medical informatics DNA Mitochondrial Biochemistry Genome Amphibians 03 medical and health sciences 0302 clinical medicine Structural Biology biology.animal Animals Repeated sequence lcsh:QH301-705.5 Molecular Biology Repetitive Sequences Nucleic Acid 030304 developmental biology 0303 health sciences mtDNA Applied Mathematics Computer Science Applications Mitogenome lcsh:Biology (General) Evolutionary biology Genome Mitochondrial lcsh:R858-859.7 Direct and inverted repeat DNA sequences DNA microarray 030217 neurology & neurosurgery Research Article |
| Zdroj: | BMC Bioinformatics BMC Bioinformatics, Vol 21, Iss 1, Pp 1-13 (2020) |
| ISSN: | 1471-2105 |
| Popis: | Background Repetitive DNA elements such as direct and inverted repeat sequences are present in every genome, playing numerous biological roles. In amphibians, the functions and effects of the repeat sequences have not been extensively explored. We consider that the data of mitochondrial genomes in the NCBI database are a valuable alternative to generate a better understanding of the molecular dynamic of the repeat sequences in the amphibians. Results This work presents the development of a strategy to identify and quantify the total amount of repeat sequences with lengths from 5 to 30 base pairs in the amphibian mitogenomes. The results show differences in the abundance of repeat sequences among amphibians and bias to specific genomic regions that are not easily associated with the classical amphibian ancestry. Conclusions Derived from these analyses, we show that great variability of the repeat sequences exists among amphibians, demonstrating that the mitogenomes of these organisms are dynamic. |
| Databáze: | OpenAIRE |
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