Synthetic Investigation toward QS-21 Analogues
| Autor: | Qing-Ju Zhang, Zhen-Ni Hu, Zhi-Yong Zeng, Jin-Xi Liao, Jian-Song Sun, De-Yong Liu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Chemistry Stereochemistry Organic Chemistry Glycosidic bond 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound Triterpenoid Glycosyl Trisaccharide Physical and Theoretical Chemistry Oleanane |
| Zdroj: | Organic Letters. 22:8613-8617 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | With glycosyl o-alkynylbenzotes as donors, a highly efficient protocol to construct the challenging glycosidic linkages at C3-OH of C23-oxo oleanane triterpenoids is disclosed, on the basis of which different strategies for the highly efficient synthesis of QS-21 analogues with the west-wing trisaccharide of QS-21 have been established. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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