Antibacterial, kinetics and bacteriolytic properties of silver(I) pyridinedicarboxylate compounds
| Autor: | M. Ignacio Azócar, Romina L. Abarca, Grace Gómez, Carla Velasquez, Marcelo J. Kogan, Maritza Páez |
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| Rok vydání: | 2013 |
| Předmět: |
Staphylococcus aureus
Silver Polymers Pyridines Ultraviolet Rays Carboxylic acid Kinetics Carboxylic Acids Bioengineering Microbial Sensitivity Tests medicine.disease_cause Coordination complex Biomaterials Minimum inhibitory concentration chemistry.chemical_compound Coordination Complexes Pyridine medicine Escherichia coli Organic chemistry chemistry.chemical_classification Antiinfective agent Chemistry Polymer Salmonella typhi Listeria monocytogenes Anti-Bacterial Agents Mechanics of Materials Nuclear chemistry |
| Zdroj: | MATERIALS SCIENCE & ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS Artículos CONICYT CONICYT Chile instacron:CONICYT |
| ISSN: | 1873-0191 |
| Popis: | Antibacterial properties of silver(I)-pyridinedicarboxylate compounds (with Pyridine-2,3-dicarboxylic(Lutidinic acid), pyridine-2,4-dicarboxylic (Quinolinic acid) and pyridine-2,5-dicarboxylic (Isocinchomeronic acid)) were studied against Escherichia coli , Listeria monocytogenes (ISP-65-08), Salmonella typhi and Staphylococcus aureus (ATCC 25923) using kinetics of grown inhibition, viability assays, minimum inhibitory concentration and optical microscopy. The 3 silver compounds were tested toward UV-radiation in order to characterize their light insensitivity for potential medical devices: UV-radiation curable polymers. Photophysical measurements show remarkable differences toward UV-radiation, which were explained based on their polymeric structures with multiple nature bonds between pyridinedicarboxylic ligands and Ag(I) centers. We found a bacteriolytic effect and differences in the antibacterial efficiency depending on the structure of the complexes and the nature of Ag X (X = oxygen and nitrogen) bonds: AgQuinol > AgLutidin > AgIsocinchom. |
| Databáze: | OpenAIRE |
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