Uterocervical angle measurement for preterm birth prediction in singleton pregnant women with no history of preterm birth and normal cervical length: A prospective cohort study
| Autor: | Rapphon Sawaddisan, Ounjai Kor-anantakul, Alan Geater, Ninlapa Pruksanusak |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Cervix Uteri Likelihood ratios in diagnostic testing Miscarriage Predictive Value of Tests Pregnancy medicine Humans Prospective Studies Prospective cohort study Receiver operating characteristic Singleton Obstetrics business.industry Uterus Infant Newborn Area under the curve Obstetrics and Gynecology Thailand medicine.disease Reproductive Medicine Cervical Length Measurement Pregnancy Trimester Second Premature Birth Gestation Term Birth Female Pregnant Women business |
| Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology. 252:30-35 |
| ISSN: | 0301-2115 |
| Popis: | Objective To evaluate the ability of second trimester uterocervical angle (UCA) to predict spontaneous preterm birth (sPTB) in low-risk singleton pregnant women. Study design Transvaginal sonographies were performed in the second trimester of 450 singleton pregnant women with no history of sPTB and no history of second trimester miscarriage with normal cervical length (CL) who attended antenatal care at Songklanagarind Hospital, a tertiary teaching hospital in southern Thailand. Gestational ages at delivery were recorded then the UCA values were evaluated according to sPTB occurrence. The differences in mean values of UCA between sPTB and full-term groups were evaluated using t-test. A receiver operating characteristics (ROC) curve was used to assess the ability of UCA to predict sPTB. Results After excluding women with unknown pregnancy outcomes or missing UCA images, the sPTB rate was 34/421 (8.1 %). In women with anteflexed uterus, the mean UCA value was wider in the sPTB group compared to those with term birth if the measurements were performed at GA 19.5–24 weeks (sPTB group, 123.4°vs controls, 104.3°; P = 0.017). The ROC curve showed an area under the curve (AUC) of 0.7045. The optimal UCA cut-off value was ≥110 degrees, which gave a sensitivity of 83.3 % and a specificity of 61.2 %. The positive predictive value (PPV) was 16.7 %, negative predictive value (NPV) 97.5 %, positive likelihood ratio (LR+) 2.2 and negative likelihood ratio (LR-) 0.3. Conclusion The UCA in the second trimester is not a good predictor of sPTB in low risk pregnant women. |
| Databáze: | OpenAIRE |
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