Comparative study of pregnancy outcomes between day 3 embryo transfer and day 5 blastocyst transfer in patients with progesterone elevation
| Autor: | Yue-Zhi Dong, Rui-Rui Li, Yihong Guo, Yingchun Su, Fan Chen, Yingpu Sun |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Pregnancy Rate Fertilization in Vitro Biochemistry Chorionic Gonadotropin Human chorionic gonadotropin Andrology Pregnancy medicine Humans Blastocyst Pregnancy outcomes Progesterone Retrospective Studies Ultrasonography Gynecology Ectopic pregnancy business.industry Biochemistry (medical) Blastocyst Transfer Pregnancy Outcome Embryo Cell Biology General Medicine medicine.disease Embryo Transfer Embryo transfer Pregnancy Ectopic medicine.anatomical_structure Female business Infertility Female |
| Zdroj: | The Journal of international medical research. 41(4) |
| ISSN: | 1473-2300 |
| Popis: | Objective To explore the effects of progesterone (P) elevation on pregnancy outcomes of day 3 embryo and day 5 blastocyst transfer. Methods Clinical outcomes (pregnancy and ectopic pregnancy rates) following day 3 embryo and day 5 blastocyst transfer cycles were retrospectively analysed. Day 3 embryo and day 5 blastocyst transfer cycles were divided into normal P level (P ≤ 1.5 ng/ml) and P elevation group (P > 1.5 ng/ml), based on the serum P level on the day of human chorionic gonadotropin (hCG) administration. Results A total of 2868 cycles were analysed. In day 3 embryo transfer cycles ( n = 2345), the clinical pregnancy rate was significantly higher in the normal P level group compared with the P elevation group (55.4% versus 46.7%, respectively) and the ectopic pregnancy rate was significantly lower in the normal P level group compared with the P elevation group (2.8% versus 7.9%, respectively). In day 5 blastocyst transfer cycles ( n = 523), there were no significant differences in the clinical pregnancy and ectopic pregnancy rates between the two groups, based on the P level. Conclusion These preliminary findings suggest that day 5 blastocyst transfer should be adopted for patients with P elevation on the day of hCG administration. |
| Databáze: | OpenAIRE |
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