Developmental and Tissue-Specific Expression of U4 Small Nuclear RNA Genes

Autor: G M Korf, I W Botros, William E. Stumph
Rok vydání: 1988
Předmět:
Zdroj: Molecular and Cellular Biology. 8:5566-5569
ISSN: 1098-5549
DOI: 10.1128/mcb.8.12.5566-5569.1988
Popis: U4 RNA is one of several small nuclear RNAs involved in the splicing of mRNA precursors. The domestic chicken has two genes per haploid genome that are capable of encoding U4 RNA. The U4X RNA gene (which encodes a sequence variant of U4 RNA that was unknown prior to the cloning of the gene) and the U4B RNA gene were both expressed in vivo in each of seven adult and three embryonic chicken tissues examined. However, the ratio of U4B RNA to U4X RNA can vary more than sevenfold in both a tissue- and stage-specific manner.
Databáze: OpenAIRE