From Pluripotent Stem Cells to Multifunctional Cordocytic Phenotypes in the Human Brain: An Ultrastructural Study

Autor:	Emil Pais, Viorel Pais, Leon Danaila
Rok vydání:	2012
Předmět:	Adult Male Pluripotent Stem Cells Pathology medicine.medical_specialty Lineage (genetic) Biology Interstitial cell Pathology and Forensic Medicine Young Adult Microscopy Electron Transmission Structural Biology medicine Humans Induced pluripotent stem cell Aged Pia mater Brain Human brain Middle Aged Phenotype medicine.anatomical_structure Microscopy Electron Scanning Ultrastructure Blood Vessels Pia Mater Stem cell
Zdroj:	Ultrastructural Pathology. 36:252-259
ISSN:	1521-0758 0191-3123
DOI:	10.3109/01913123.2012.669451
Popis:	Light microscopy and transmission electron microscopy were used to investigate surgical cases in a variety of pathological conditions (thromboses, tumors, cerebrovascular malformations, Moyamoya disease) to identify and characterize different phenotypes belonging to a new interstitial cell recently described ultrastructurally in the brain and here named "cordocyte." Also, this work is an attempt to identify and characterize precursor/stem cells for cordocytic lineage in the perivascular areas, within perivascular nerves and pia mater (now considered a cordocytic-vascular tissue). Unexpected relationships and functions emerge from observations concerning these phenotypes, almost ubiquitous, but not yet fully studied in the brain.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b4bd348db231d19e7884bd8772e187 https://doi.org/10.3109/01913123.2012.669451 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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