Auts2 regulated autism-like behavior, glucose metabolism and oxidative stress in mice

Autor: Min, Liu, Yimeng, Chen, Miao, Sun, Yingjie, Du, Yafan, Bai, Guiyu, Lei, Congya, Zhang, Mingru, Zhang, Yue, Zhang, Chunhua, Xi, Yulong, Ma, Guyan, Wang
Rok vydání: 2023
Předmět:
Zdroj: Experimental Neurology. 361:114298
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2022.114298
Popis: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by abnormal social behavior and communication. The autism susceptibility candidate 2 (AUTS2) gene has been associated with multiple neurological diseases, including ASD. Glucose metabolism plays an important role in social behaviors associated with ASD, but the potential role of AUTS2 in glucose metabolism has not been studied. Here, we generated Auts2
Databáze: OpenAIRE