Clinical outcomes and prognostic factors of robotic assisted rectal cancer resection alone versus robotic rectal cancer resection with natural orifice extraction: a matched analysis

Autor:	Penghui He, Shanping Ye, Taiyuan Li, Rui Luo, Weiquan Zhu, Cheng Tang, Zhikai Wan, Dongning Liu, Xiong Lei
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Adult Male Natural Orifice Endoscopic Surgery medicine.medical_specialty Surgical stress Time Factors Cancer therapy Adolescent Visual analogue scale Robotic assisted Colorectal cancer lcsh:Medicine Natural orifice Article Resection 03 medical and health sciences Young Adult 0302 clinical medicine Robotic Surgical Procedures Medicine Humans Rectal cancer lcsh:Science Nose Digestive System Surgical Procedures Aged Multidisciplinary business.industry Rectal Neoplasms lcsh:R Middle Aged medicine.disease Prognosis Surgery medicine.anatomical_structure Treatment Outcome 030220 oncology & carcinogenesis T-stage 030211 gastroenterology & hepatology Female Laparoscopy lcsh:Q Safety business
Zdroj:	Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020) Scientific Reports
ISSN:	2045-2322
DOI:	10.1038/s41598-020-69830-1
Popis:	Robotic rectal cancer resection with natural orifice extraction is a recently developed minimally invasive surgery used in the treatment of patients with rectal cancer. However, its safety and feasibility remain undiscussed and controversial. This study reported the clinical outcomes and prognostic factors pertaining to traditional robotic assisted rectal cancer resection alone against that of robotic rectal cancer resection with natural orifice extraction to provide a discussion on this issue. 49 patients who underwent robotic rectal cancer resection with natural orifice extraction and 49 matched patients who underwent conventional robotic assisted rectal cancer resection were systematically analyzed in this study. Regarding the baseline characteristics, after matching, no significant differences were observed between the natural orifice specimen extraction (NOSE) group and the robotic assisted rectal cancer resection (RARC) group. Patients in the NOSE group had a reduced visual analog scale (p p = 0.002) and suffered less surgical stress than those in the RARC group. Moreover, 4 complications were observed in the NOSE group and 7 complications in the RARC group with no significant difference (p = 0.337) in terms of complications. The two groups had a similar survival outcomes, where the 3-year overall survival (p = 0.738) and 3-year progression-free survival (p = 0.986) were all comparable between the two groups. Histological differentiation and T stage could be regarded as independent prognostic factors for 3-year overall survival and 3-year progression-free survival. Robotic rectal cancer resection with natural orifice extraction is a safe and feasible minimally invasive surgery for patients suffering from rectal cancer as it encompasses considerable several advantages. Histological differentiation and T stage may serve as independent prognostic factors for 3-year overall survival and 3-year progression-free survival.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b34f2c6cc9337cfac1ab995d44b1cc http://link.springer.com/article/10.1038/s41598-020-69830-1 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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