Distribution and Functional Consequences of Somatic MAP2K1 Variants in Affected Skin Associated with Bone Lesions in Melorheostosis
| Autor: | Françoise Meylan, Andrew C. Warner, Joan C. Marini, Alison A. McBride, Timothy Bhattacharyya, Elijah F. Edmondson, Heeseog Kang, Aleksandra Ivovic, James D. Katz, Casey A. Rimland, Edward W. Cowen, Eric P. Hanson, Richard M. Siegel, Smita Jha, Eileen Lange |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male MAPK/ERK pathway Intravital Microscopy Melorheostosis Somatic cell Biopsy Extracellular signal-regulated kinases DNA Mutational Analysis Primary Cell Culture MAP Kinase Kinase 1 Dermatology Biology Biochemistry Bone and Bones Article Young Adult MAP2K1 medicine Humans Distribution (pharmacology) Prospective Studies Molecular Biology Cells Cultured Skin Cell Biology Fibroblasts Middle Aged medicine.disease Cell biology Mapk erk kinase Bone lesion Female |
| Zdroj: | J Invest Dermatol |
| ISSN: | 0022-202X |
| DOI: | 10.1016/j.jid.2020.06.036 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|