Clinically relevant treatment considerations regarding lithium use in bipolar disorder
| Autor: | Tara Richardson, Matthew Macaluso |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Suicide Prevention
medicine.medical_specialty Bipolar Disorder Lithium (medication) medicine.drug_class Toxicology 03 medical and health sciences 0302 clinical medicine Antimanic Agents Bipolar mania medicine Humans Drug Interactions In patient LITHIUM USE Bipolar disorder Psychiatry Pharmacology business.industry Mood stabilizer General Medicine medicine.disease 030227 psychiatry Mood disorders Practice Guidelines as Topic Lithium Compounds Drug Monitoring medicine.symptom business Mania 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Expert Opinion on Drug Metabolism & Toxicology. 13:1105-1113 |
| ISSN: | 1744-7607 1742-5255 |
| DOI: | 10.1080/17425255.2017.1386653 |
| Popis: | Introduction: The goal of this paper is to provide a practical, clinically oriented review of lithium, a salt widely used to treat mania since the 1870s and formally approved as a mood stabilizer in 1970. Although lithium is still considered a first-line treatment for bipolar mania in most practice guidelines, its use may be overshadowed by newer psychotropic medications.Areas covered: This paper addresses the historical use of lithium, modern indications for its use, guidelines for prescribing and monitoring continued lithium use, drug-drug interactions, and pharmacodynamics/pharmacokinetic properties. The paper also reviews the unique properties of lithium and their potential clinical importance.Expert opinion: While the use of lithium does involve some unique risks to the patient, it may also has some unique advantages in certain patient populations. Two major findings that make lithium unique are its potential neuroprotective benefits and decreased risk of suicide in patients with mood disorders. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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