Factors Associated With Peripartum Virologic Suppression in Eastern Cape Province, South Africa: A Retrospective Cross-Sectional Analysis
| Autor: | Anthony Idowu Ajayi, Chikwelu Larry Obi, Daniel Ter Goon, Benson Chucks Iweriebor, John S. Lambert, Anthony I. Okoh, Nonkosi Selanto-Chairman, Gordana Avramovic, Oladele Vincent Adeniyi, Craig Carty |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Anti-HIV Agents Cross-sectional study antiretroviral therapy HIV Infections Viremia Prenatal care 030204 cardiovascular system & hematology in utero transmission South Africa 03 medical and health sciences 0302 clinical medicine Pregnancy Peripartum Period Humans Medicine 030212 general & internal medicine Retrospective Studies business.industry Obstetrics mother-to-child transmission HIV Odds ratio Viral Load medicine.disease Infectious Disease Transmission Vertical Confidence interval Major Articles and Commentaries AcademicSubjects/MED00290 Cross-Sectional Studies Infectious Diseases Cohort Female business Viral load |
| Zdroj: | Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America |
| ISSN: | 1537-6591 1058-4838 |
| Popis: | Background This study describes the characteristics of pregnant women on antiretroviral therapy (ART) and the rate of peripartum virologic suppression in a large prevention of mother-to-child transmission cohort who delivered in some selected maternity centers in Eastern Cape Province, South Africa. In addition, the study examines the factors associated with virologic suppression in the cohort. Methods This multicenter, retrospective cross-sectional analysis included medical data of 1709 women with human immunodeficiency virus between September 2015 and May 2016 in Eastern Cape Province. The main outcome measure was the rate of peripartum virologic suppression, defined as viral load (VL) In this multicenter, cross-sectional analysis of women with human immunodeficiency virus, younger age (18–24 years) and smoking during pregnancy were significantly associated with lower odds of peripartum virologic suppression. Self-reported complete adherence was associated with higher odds of peripartum viral load suppression. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|