Contemporary clinical management of isolated high-grade prostatic intraepithelial neoplasia
| Autor: | G Godoy, S S Taneja |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
Oncology Cancer Research medicine.medical_specialty Pathology Biopsy Urology Extended biopsy Risk Assessment Prostate cancer Internal medicine Carcinoma Humans Medicine High-grade prostatic intraepithelial neoplasia Neoplasm Staging Prostatic Intraepithelial Neoplasia Intraepithelial neoplasia medicine.diagnostic_test business.industry Prostatic Neoplasms Cancer Prognosis medicine.disease Natural history Disease Progression business |
| Zdroj: | Prostate Cancer and Prostatic Diseases. 11:20-31 |
| ISSN: | 1476-5608 1365-7852 |
| DOI: | 10.1038/sj.pcan.4501014 |
| Popis: | High-grade prostatic intraepithelial neoplasia (HGPIN) is a premalignant lesion associated with increased risk of coexistent cancer or delayed progression to carcinoma. Extended biopsy schemes have improved the ability to rule out concurrent cancers, increased the detection of isolated HGPIN and removed the routine necessity for immediate repeat biopsy. As the natural history of HGPIN is poorly defined, and no non-invasive marker allows monitoring of progression to cancer, routine delayed interval biopsy should be considered in all patients. In this article, we present an overview of the existing literature on HGPIN and a proposed strategy for clinical management. |
| Databáze: | OpenAIRE |
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