MicroRNA‑194‑5p attenuates hypoxia/reoxygenation‑induced apoptosis in H9C2 cardiomyocytes by inhibiting the over‑activation of RAC1 protein

Autor:	Cuie, Li, Yinghua, Li, Yanping, Li, Yudi, Wang, Yirong, Teng, Yinglu, Hao
Rok vydání:	2022
Předmět:	rac1 GTP-Binding Protein Cancer Research Apoptosis Biochemistry Cell Hypoxia Cell Line Rats MicroRNAs Oncology Genetics Humans Animals Molecular Medicine Myocytes Cardiac Hypoxia Reactive Oxygen Species Molecular Biology
Zdroj:	Molecular Medicine Reports. 27
ISSN:	1791-3004 1791-2997
DOI:	10.3892/mmr.2022.12920
Popis:	Ras‑related C3 botulinum toxin substrate 1 (RAC1), a member of the Rac family of guanosine triphosphate phosphohydrolases, has been suggested to be a regulator of myocardial injury during ischemia and reperfusion (I/R). Whether microRNAs (miRs) are involved in the regulation of the aforementioned process remains to be elucidated. In the present study, an
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48980518b0a59eec9ebbf367058e5b9a https://doi.org/10.3892/mmr.2022.12920 Zobrazit plný text záznamu