In vitro binding of amantadine to plasma proteins
| Autor: | Ing Ts, P J Cheng, Liu P, L S Soung, R Jeevanandhan, S Galinis, Daugirdas Jt |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Pharmacology
Chromatography Plasma samples Chemistry Amantadine Amantadine Hydrochloride Ultrafiltration Plasma protein binding Blood Proteins In Vitro Techniques Blood proteins In vitro binding Ultrafiltration (renal) medicine Humans Pharmacology (medical) Neurology (clinical) Blood bank Serum Albumin medicine.drug Protein Binding |
| Zdroj: | Clinical neuropharmacology. 7(2) |
| ISSN: | 0362-5664 |
| Popis: | In vitro binding of amantadine to plasma protein was assessed by ultrafiltration of plasma samples (from a blood bank) to which amantadine hydrochloride had been added. Approximately two-thirds of the amantadine was found to be protein-bound. The degree of protein binding was constant over a plasma amantadine concentration range of 100-2,000 ng/ml. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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