Supplemental Figures 1-5 from Targeting Lineage-specific MITF Pathway in Human Melanoma Cell Lines by A-485, the Selective Small-molecule Inhibitor of p300/CBP

Autor: Lloyd T. Lam, Tamar Uziel, Albert Lai, Anahita Bhathena, Xin Lu, Loren M. Lasko, Paul Hessler, Ziping Yang, Valerie Robinson, Yupeng He, Rui Wang
Rok vydání: 2023
DOI: 10.1158/1535-7163.22504405
Popis: Suppl. Figure 1. Dependency of human melanoma cell lines on MITF; Suppl. Figure 2. A-485 treatment reduces viability of primary melanoma cell line; Suppl. Figure 3. A-485 treatment does not induce apoptosis in melanoma cells; Suppl. Figure 4. A-485 treatment does not increase invasiveness in melanoma cells; Suppl. Figure 5. MITF gene expression and copy number is associated with A-485-induced senescence
Databáze: OpenAIRE