Venous thrombosis after long-haul flights
| Autor: | Roswitha Frommhold, Hans-Egbert Schroeder, Kai Halbritter, Jan Beyer, Thomas Schwarz, Sebastian Schellong, Eberhard Kuhlisch, Florian Lenz, Gabriele Siegert, Siegmund Gehrisch, Wolfram Oettler |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Aircraft medicine.drug_class medicine.medical_treatment Compression stockings Risk Factors Internal medicine Internal Medicine medicine Humans Prospective Studies Risk factor Prospective cohort study Muscle Skeletal Selection Bias Aged Aged 80 and over Venous Thrombosis Travel business.industry Incidence Anticoagulant Syndrome Middle Aged medicine.disease Thrombosis Surgery Pulmonary embolism Venous thrombosis Embolism Research Design Case-Control Studies Cardiology Female business Pulmonary Embolism |
| Zdroj: | Archives of internal medicine. 163(22) |
| ISSN: | 0003-9926 |
| Popis: | Background The risk for venous thromboembolism after long-haul flights represents a controversial issue. The aim of our study was to assess the incidence of venous thrombosis associated with long-haul flights in a prospective, controlled cohort study. Methods We included 964 passengers returning from long-haul flights (flight duration, ≥8 hours) and 1213 nontraveling control subjects. We excluded participants who were being treated with anticoagulant drugs or who used compression stockings. Main outcome measures were the incidence of ultrasonographically diagnosed thrombosis in the calf muscle and deep veins, symptomatic pulmonary embolism, and death. Results We diagnosed venous thrombotic events in 27 passengers (2.8%) and 12 controls (1.0%) (risk ratio [RR], 2.83; 95% confidence interval [CI], 1.46-5.49). Of these, 20 passengers (2.1%) and 10 controls (0.8%) presented with isolated calf muscle venous thrombosis (RR, 2.52; 95% CI, 1.20-5.26), whereas 7 passengers (0.7%) and 2 controls (0.2%) presented with deep venous thrombosis (RR, 4.40; 95% CI, 1.04-18.62). Symptomatic pulmonary embolism was diagnosed in 1 passenger with deep venous thrombosis ( P = .44). All of these individuals had normal findings at baseline ultrasonography. Passengers with isolated calf muscle venous thrombosis or deep venous thrombosis had at least 1 risk factor for venous thrombosis (>45 years of age or elevated body mass index in 21 of 27 passengers). The follow-up after 4 weeks revealed no further venous thromboembolic event. Conclusions Long-haul flights of 8 hours and longer double the risk for isolated calf muscle venous thrombosis. This translates into an increased risk for deep venous thrombosis as well. In our study, flight-associated thrombosis occurred exclusively in passengers with well-established risk factors for venous thrombosis. |
| Databáze: | OpenAIRE |
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