Clustering of eyes with age-related macular degeneration or pachychoroid spectrum diseases based on choroidal thickness profile
| Autor: | Jaeryung Oh, Boram Lee, Edward Kang, Youngho Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty genetic structures Science Retinal Drusen Diseases Pathogenesis Article 03 medical and health sciences Macular Degeneration 0302 clinical medicine Medical research Age related Ophthalmology medicine Humans Aged Retrospective Studies Aged 80 and over Multidisciplinary business.industry Choroid Macular degeneration Soft drusen Middle Aged medicine.disease eye diseases Reticular pseudodrusen 030104 developmental biology 030221 ophthalmology & optometry Medicine Female sense organs business Tomography Optical Coherence Biomarkers |
| Zdroj: | Scientific Reports Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021) |
| ISSN: | 2045-2322 |
| Popis: | Choroidal changes have been suggested to be involved in the pathophysiology of both age-related macular degeneration (AMD) and pachychoroid spectrum diseases (PSD). To find out the choroidal characteristics of each disease groups, various groups of AMD and PSD were classified into several clusters according to choroidal profiles based on subfoveal choroidal thickness (CT), peripapillary CT, the ratio of subfoveal CT to peripapillary CT and age. We retrospectively analyzed 661 eyes, including 190 normal controls and 471 with AMD or PSDs. In the AMD groups, eyes with soft drusen or reticular pseudodrusen were belonged to the same cluster as those with classic exudative AMD (all p p p |
| Databáze: | OpenAIRE |
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