Low-frequency and very low-intensity ultrasound decreases blood pressure in hypertensive subjects with type 2 diabetes
| Autor: | Tomoe Yamazaki, Katsunori Nonogaki, Nariki Kubota, Shuichi Katoh, Mari Murakami, Miki Hazama, Nobuyuki Tsujita, Noriko Satoh, Kouji Takeda |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Ultrasonic Therapy Diastole Blood Pressure Type 2 diabetes 030204 cardiovascular system & hematology Placebo 03 medical and health sciences 0302 clinical medicine Forearm Internal medicine medicine Humans 030212 general & internal medicine Ultrasound irradiation Aged business.industry Ultrasound Middle Aged medicine.disease Surgery Pulse pressure Blood pressure medicine.anatomical_structure Diabetes Mellitus Type 2 Ultrasonic Waves Hypertension Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | International Journal of Cardiology. 215:147-149 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/j.ijcard.2016.04.062 |
| Popis: | Background Despite lifestyle interventions and various types of anti-hypertension agents, hypertension remains difficult to control in some patients with type 2 diabetes. As a noninvasive device-based approach for the treatment of clinic hypertension, we examined the effects of low-frequency and low-intensity ultrasound (500 or 800kHz, 25mW/cm 2 ) applied to the forearm on blood pressure (BP) and pulse rate in Japanese subjects with type 2 diabetes and hypertension. Methods We examined the effects of low-frequency and low-intensity ultrasound (500 or 800kHz, 25mW/cm 2 ) applied to the forearm on BP, pulse rate, and pulse pressure in 212 Japanese subjects (82 men and 130 women; mean age±SE, 65±1years) with type 2 diabetes and hypertension (systolic BP>140mmHg). The subjects were treated with anti-hypertension agents. Results Systolic and diastolic BP, pulse rate, pulse pressure in the 800-kHz ultrasound treatment group were significantly lower than the baseline values in hypertensive subjects with type 2 diabetes, and lower than those of placebo controls. In addition, systolic and diastolic BP, pulse rate, and pulse pressure in the 500-kHz ultrasound treatment group were significantly lower than the baseline values in hypertensive subjects with type 2 diabetes, and systolic BP, pulse rate, and pulse pressure were significantly lower than those of placebo controls. Conclusions Low-frequency (800kHz or 500kHz) and low-intensity (25mW/cm 2 ) ultrasound irradiation to the forearm might have potential usefulness as a therapeutic application for clinic hypertension in subjects with type 2 diabetes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect