Primary neuroendocrine tumor of the sacrum: case report and review of the literature
| Autor: | Pauline Beaussart, Fanny Dujardin, Denis Mulleman, Gonzague de Pinieux, Anne de Muret, Eric Waynberger, Philippe Rosset |
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| Přispěvatelé: | Cambefort, Jeanne, Génétique, immunothérapie, chimie et cancer (GICC), UMR 6239 CNRS [2008-2011] (GICC UMR 6239 CNRS), Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2009 |
| Předmět: |
Male
musculoskeletal diseases Sacrum medicine.medical_specialty medicine.medical_treatment Primary carcinoid [SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine Neuroendocrine tumors [SDV.IB.MN] Life Sciences [q-bio]/Bioengineering/Nuclear medicine Lesion 03 medical and health sciences 0302 clinical medicine Neuroendocrine tumor Humans Medicine Radiology Nuclear Medicine and imaging Aged Spinal Neoplasms business.industry medicine.disease Magnetic Resonance Imaging Low back pain Primary tumor 3. Good health Surgery body regions Radiation therapy Neuroendocrine Tumors 030220 oncology & carcinogenesis Orthopedic surgery Radiology medicine.symptom Tomography X-Ray Computed business Sacrococcygeal teratoma 030217 neurology & neurosurgery MRI |
| Zdroj: | Skeletal Radiology Skeletal Radiology, Springer Verlag, 2009, 38 (8), pp.819-823 |
| ISSN: | 1432-2161 0364-2348 |
| Popis: | International audience; Primary carcinoid tumor (well-differentiated neuroendocrine tumor) of the bone involving the sacrum is extremely rare. We report the case of a 72-year-old man who presented with a 20-year history of intermittent low back pain and was found to have an intraosseous sacral mass on imaging. A needle biopsy revealed that this lesion was a well-differentiated neuroendocrine tumor. Workup did not show any primary tumor or other metastatic disease. There was no associated tailgut cyst or sacrococcygeal teratoma. The lesion was treated with radiation therapy because a surgical approach was rejected. The patient is free of metastatic disease after 28 years evolution of the lesion, retrospectively seen to be present on a conventional radiography performed in 1980. A review of the literature revealed 20 case reports of neuroendocrine tumors arising from the presacral region (with or without associated tailgut cyst or sacrococcygeal teratoma) and sometimes extending to the sacrum. One additional case was located within the neural canal and involved the sacrum, the presacral region, and the rectal wall. Our case is the only tumor arising primarily from the sacrum. The long evolution of this lesion without any other location makes metastatic disease very improbable and this case appears to be a unique example of primary intraosseous sacral carcinoid tumor. |
| Databáze: | OpenAIRE |
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