Outbreak of vancomycin-resistant enterococci (VRE) in a hematological oncology ward and hygienic preventive measures. A long-term study
| Autor: | Hans-Heinrich Wolf, Julia Okpara-Hofmann, Ingo Klare, Georg Daeschlein, Martin Knoll, Marianne Borneff-Lipp, Dorothea Wilhelms |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Living environment media_common.quotation_subject Risk Assessment Disease Outbreaks Risk groups Hygiene Risk Factors Internal medicine Germany Oncology Service Hospital Prevalence Medicine Infection control Humans Mass Screening Longitudinal Studies Practice Patterns Physicians' Gram-Positive Bacterial Infections media_common business.industry Outbreak Vancomycin-Resistant Enterococci Vancomycin Resistance Hematology biochemical phenomena metabolism and nutrition University hospital Anti-Bacterial Agents Long term learning Treatment Outcome Hematologic Neoplasms Practice Guidelines as Topic business Enterococcus |
| Zdroj: | Onkologie. 28(4) |
| ISSN: | 0378-584X |
| Popis: | Background: We report on two endemic outbreaks of VRE (vancomycin-resistant enterococci, vanA type Ente-rococcus faecium) on a hematological oncology ward in a university hospital and a new strategic concept to fight against spread of VRE. Patients and Methods: During management of the outbreak, a total of 1,124 patients and 1,700 specimens were investigated from June 1999 to December 2001. Protective measures were instituted. Intensive prophylactic infection control was practiced until December 2003. Results: Of the 1,124 patients, 44 were VRE-positive. From 1,700 environment speci-mens, 110 VRE isolates were obtained from the inani-mate environment, 5 from the living environment. Mole-cular biological typing identified 5 different clones which had spread on the ward in different locations. Conclu-sion: The study shows the need for prophylactic microbi-ological screening investigations in the risk group of hematological oncology patients and consistent imple-mentation of protective hygiene measures to prevent the spread of multiresistant infectious pathogens on risk wards. It is also shown that intervention can to control such an endemic outbreak. |
| Databáze: | OpenAIRE |
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