Enlarged mediastinal lymph nodes in bronchogenic carcinoma: assessment with dynamic contrast-enhanced MR imaging. Work in progress
| Autor: | Y. Menu, M C Dombret, G Murciano, Philippe Soyer, M Aubier, A Sautet, Jean-Pierre Laissy, P Gay-Depassier |
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| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty Lung Neoplasms Contrast Media Meglumine medicine Carcinoma Organometallic Compounds Humans Radiology Nuclear Medicine and imaging Lymph node Aged Lung medicine.diagnostic_test Epithelioma business.industry Mediastinum Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Carcinoma Bronchogenic Cardiothoracic surgery Coronal plane Lymphatic Metastasis Carcinoma Squamous Cell Female Radiology Lymph Lymph Nodes business |
| Zdroj: | Radiology. 191(1) |
| ISSN: | 0033-8419 |
| Popis: | To determine whether dynamic contrast material-enhanced magnetic resonance (MR) imaging can help differentiate between malignant and benign mediastinal lymph nodes (MLNs) in bronchogenic carcinoma.Nine patients with biopsy-proved lung carcinoma underwent dynamic contrast-enhanced MR imaging before undergoing thoracic surgery. MR studies included spin-echo, electrocardiographically gated axial and coronal sequences and transaxial gradient-echo breath-hold sequences, which were performed after administration of a bolus of gadoterate meglumine. The enhancement curves were established on the basis of mean signal intensities from regions of interest at the level of tumor and the enlarged MLN. MR images were compared with pathologic specimens obtained at surgical resection.Metastatic MLNs exhibited their peak enhancement at 60-80 seconds, with a slow decrease until 6 minutes. Granulomatous and anthracotic lymph nodes displayed a slight enhancement, with no peak within 6 minutes (P.01).Dynamic contrast-enhanced MR images may provide informative data about the nature of enlarged MLNs in the preoperative assessment of lung carcinoma. Further studies are needed to investigate its usefulness in clinical practice. |
| Databáze: | OpenAIRE |
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