| Autor: |
Phillip A. Dennis, Joell J. Gills, M. Christine Hollander, Regan M. Memmott, Ajaikumar B. Kunnumakkara, Hiroshi Kitagawa, Matthew Dallos, Brendan J. Quinn |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1940-6207.22525208.v1 |
| Popis: |
PDF file - 653K, Supplemental Figure 1. Densitometry was peformed on the immunoblots from Figures 2C (A) and 2E (B) using Image J software. Supplemental Figure 2. A/J mice were treated with metformin (250 mg/kg ip qdX3) as in Figure 2C. Supplemental Figure 3. A/J mice were exposed to NNK (100 mg/kg ip qdX3) to induce lung tumorigenesis, and then treated with 5 mg/mL metformin in drinking water for 13 weeks. Supplemental Figure 4. A/J mice (no NNK) were treated with or without 5mg/mL metformin in their drinking water for 13 weeks, and lungs were harvested as previously described. Supplemental Figure 5. (A) Absolute levels of liver metformin uptake between the three routes of administration. (B) Absolute metformin uptake in tissues, converted to molarity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
