How should incidental NEN of the pancreas and gastrointestinal tract be followed?
| Autor: | Francesca Della Sala, Massimo Falconi, Riccardo Ariotti, Francesca Muffatti, Stefano Partelli, Valentina Andreasi |
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| Přispěvatelé: | Ariotti, R., Partelli, S., Muffatti, F., Andreasi, V., Sala, F. D., Falconi, M. |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Primary disease Asymptomatic 03 medical and health sciences 0302 clinical medicine Endocrinology Incidental NEN medicine Humans Large intestine Gastrointestinal Neoplasms Gastrointestinal tract business.industry Stomach Incidence (epidemiology) NEN NEN follow-up Conservative treatment Neuroendocrine neoplasm Pancreatic Neoplasms Neuroendocrine Tumors medicine.anatomical_structure Pancreatic NEN 030220 oncology & carcinogenesis Gastrointestinal Neoplasm Radiology medicine.symptom business Pancreas Neuroendocrine Tumor Human |
| Popis: | Neuroendocrine gastro-entero-pancreatic neoplasms (GEP-NENs) constitute a heterogeneous group of tumors, whose incidence has increased over the years. The most frequent site for primary disease is the stomach followed by small and large intestine, and pancreas. In the last decade, a dramatic growing in the incidence of small, incidental GEP-NENs has been recorded. In parallel, an increasing attitude toward more conservative approaches instead of surgical management has being widely spreading. This is particularly true for small, asymptomatic, pancreatic NEN as for these tumor forms an active surveillance has proven to be safe and feasible. Primary site and biological features of the neoplasms lead to different strategies and indications for surveillance and follow-up. This review focuses on the current evidence on modality and timing of surveillance and conservative treatment of incidentally discovered lesions. |
| Databáze: | OpenAIRE |
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