Identification of Two Novel Single Nucleotide Polymorphisms in the Promoter Region of the Pig AMP Deaminase 1 Gene Associated with Carcass Traits
| Autor: | Zhe Chao, Linjie Wang, Yan Wang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Meat Swine Energy metabolism Gene Expression Single-nucleotide polymorphism Biology Polymorphism Single Nucleotide AMP Deaminase Quantitative Trait Heritable Genetics SNP Animals Body Fat Distribution Muscle Skeletal Promoter Regions Genetic Molecular Biology Gene Alleles Purine nucleotide interconversion Base Sequence Body Weight Promoter AMP deaminase Cell Biology General Medicine Phenotype Adipose Tissue Haplotypes Genetic Loci Identification (biology) Female |
| Zdroj: | DNA and cell biology. 37(11) |
| ISSN: | 1557-7430 |
| Popis: | The AMP deaminase 1 (AMPD1) gene plays an important role in purine nucleotide interconversion and energy metabolism. In this study, two novel single nucleotide polymorphisms (SNPs) (g.-626 G A and g.-566 AG) were detected in the proximal promoter region of the AMPD1 gene. The Chinese indigenous pig breeds (Meishan and Tongcheng) had higher frequencies of the G and A alleles than Western meat-type breeds (Landrace and Large White) at the g.-626 G A and g.-566 AG loci. The transcriptional activity of the AMPD1 promoter carrying the haplotype H1 (A |
| Databáze: | OpenAIRE |
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