Evoked Potentials During Peripheral Stimulation Confirm Electrode Location in Thalamic Subnuclei in Children With Secondary Dystonia
| Autor: | Ruta Deshpande, Terence D. Sanger, Estefania Hernandez-Martin, Enrique Arguelles |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Movement disorders Deep brain stimulation Adolescent Deep Brain Stimulation medicine.medical_treatment Thalamus Stimulation 03 medical and health sciences 0302 clinical medicine Basal ganglia Humans Medicine Child Evoked Potentials Dystonia medicine.diagnostic_test business.industry Reproducibility of Results Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Electrodes Implanted Electrophysiology 030104 developmental biology Dystonic Disorders Pediatrics Perinatology and Child Health Female Neurology (clinical) medicine.symptom Tomography X-Ray Computed business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Journal of Child Neurology. 35:799-807 |
| ISSN: | 1708-8283 0883-0738 |
| Popis: | Deep brain stimulation is an elective surgical intervention that improves the function and quality of life in children with dystonia and other movement disorders. Both basal ganglia and thalamic nuclei have been found to be relevant targets for treatment of dystonia in children, including the ventral intermediate nucleus of the thalamus, in which stimulation can control dystonic spasms. Electrophysiological confirmation of correct electrode location within the ventralis intermediate nucleus is thus important for the success of the surgical outcome. The present work shows the evoked potentials response during contralateral median-nerve stimulation at the wrist at low frequency (9 Hz) provides physiological evidence of the electrode’s localization within the thalamus. We show the correlation between evoked potentials and magnetic resonance imaging (MRI) and computed tomography (CT) in 14 children undergoing implantation of deep brain stimulation electrodes for secondary dystonia. High fidelity and reproducibility of our results provides a new approach to ensure the electrode localization in the thalamic subnuclei. |
| Databáze: | OpenAIRE |
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