Unsupervised bubble calorimetry analysis: Surface tension from isothermal titration calorimetry

Autor: Philippe Dumas, Adrián Velázquez-Campoy, Alfredo Amigo, Ángel Piñeiro, Margarida Bastos, Pablo F. Garrido
Přispěvatelé: Universidade de Santiago de Compostela. Departamento de Física Aplicada, univOAK, Archive ouverte, Universidade de Santiago de Compostela [Spain] (USC ), Faculdade de Ciências da Universidade do Porto (FCUP), Universidade do Porto = University of Porto, University of Zaragoza - Universidad de Zaragoza [Zaragoza], Instituto de Investigación Sanitaria de Aragón [Zaragoza] (IIS Aragón), Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (CIBERehd), Liver Unit, Clínica Universitaria, CIBER-EHD, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Fundação para a Ciência e a Tecnologia (Portugal), European Commission
Rok vydání: 2022
Předmět:
Zdroj: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Journal of Colloid and Interface Science
Journal of Colloid and Interface Science, 2021, 606 (Part 2), pp.1823-1832. ⟨10.1016/j.jcis.2021.08.115⟩
Digital.CSIC. Repositorio Institucional del CSIC
ISSN: 0021-9797
1095-7103
Popis: 10 pags, 8 figs. -- Supplementary data to this article can be found online at https://doi.org/10.1016/j.jcis.2021.08.115.
Hypothesis: The injection of air into the sample cell of an isothermal titration calorimeter containing a liquid provides a rich-in-information signal, with a periodic contribution arising from the creation, growing and release of bubbles. The identification and analysis of such contributions allow the accurate determination of the surface tension of the target liquid. Experiments: Air is introduced at a constant rate into the sample cell of the calorimeter containing either a pure liquid or a solution. The resulting calorimetric signal is analyzed by a new algorithm, which is implemented into a computational code. Findings: The thermal power generated by our experiments is often noisy, thus hiding the periodic signal arising from the bubbles’ formation and release. The new algorithm was tested with a range of different of calorimetric raw data, some of them apparently being just noise. In all cases, the contribution of the bubbles to the signal was isolated and the corresponding period was successfully determined in an automated way. It is also shown that two reference measurements suffice to calibrate the instrument at a given temperature, regardless the injection rate, allowing the direct determination of surface tension values for the liquid contained in the sample cell.
The authors thank the financial support of the Spanish Ministry of Economy and Competitiveness (projects MAT2015-71826-P to A. P. and BFU2016-78232-P to A.V.C.), the Agencia Estatal de Investigacion (AEI) (project PID2019-111327GB-I00 to A. P.) and Fundacao para a Ciencia e Tecnologia (FCT), Portugal, for CIQUP (project UIDB/00081/2020 to M.B.). P. F. G. thanks the Spanish Ministry of Economy and Competitiveness and the European Social Fund for his predoctoral research grant, reference BES-2016076761. These research projects were partially supported by European ERDF Funds (MCIU/AEI/FEDER, EU). Facilities provided by the Galician Supercomputing Centre (CESGA) are also acknowledged.
Databáze: OpenAIRE
Externí odkaz: